Antinociceptive and Anti-Inflammatory Effects of Saponin and Iridoid Glycosides from Verbascum pterocalycinum var. mutense Hub.-Mor.

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Antinociceptive and anti-inflammatory effects of saponin and iridoid glycosides from Verbascum pterocalycinum var. mutense Hub.-Mor.

The anti-inflammatory and antinociceptive properties of four major compounds from the flowers of Verbascum pterocalycinum var. mutense were investigated. Saponin glycosides called ilwensisaponin A and C and iridoid glycosides known as ajugol and picroside IV were isolated from the methanolic extract. A dose-related anti-inflammatory and antinociceptive response were obtained in this study at do...

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Iridoid and Phenylethanoid Glycosides from Verbascum lasianthum

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Two new phenylethanoid glycosides integrifoliosides A (2) and B (3), along with a known phenylethanoid glycoside alyssonoside (1) and a flavone glucoside chrysoeriol-7-O-beta-D-glucopyranoside (4) were isolated from the aerial parts of Phlomis integrifolia. The structures of the new compounds were identified as 3,4-dihydroxy-beta-phenylethoxy-O-beta-D-apiofuranosyl-(1 --> 4)-alpha-L-rhamnopyran...

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Anti-inflammatory and antinociceptive potential of major phenolics from Verbascum salviifolium Boiss.

The potential effects of flavonoids, phenylethanoid and neolignan glycosides from the aerial parts of Verbascum salviifolium Boiss. were studied in the p-benzoquinone-induced writhing reflex, for the assessment of the antinociceptive activity, and in carrageenan- and PGE1-induced hind paw edema and 12-O-tetradecanoyl-13-acetate (TPA)-induced ear edema models in mice, for the assessment of the a...

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Evaluation of antinociceptive and anti-inflammatory activities of a new triterpene saponin from Bauhinia variegata leaves.

A new triterpene saponin, named as 23-hydroxy-3alpha-[O-alpha-L-1C4-rhamnopyranosyl-(1"-->4')-O-alpha-L-4C1-arabinopyranosyl-oxy]olean-12-en-28-oic acid O-alpha-L-1C4-rhamnopyranosyl-(1""'-->4"")-O-beta-D-4C1-glucopyranosyl-(1""-->6"')-O-beta-D-4C1-glucopyranosyl ester (9), was isolated from the leaves of Bauhinia variegata Linn. In addition, six flavonoid compounds along with two cinnamic acid...

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ژورنال

عنوان ژورنال: Zeitschrift für Naturforschung C

سال: 2007

ISSN: 1865-7125,0939-5075

DOI: 10.1515/znc-2007-11-1207